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Genetic relationship between the HA genes of type A influenza viruses isolated in off-seasons and later epidemic seasons

Identifieur interne : 002025 ( Main/Exploration ); précédent : 002024; suivant : 002026

Genetic relationship between the HA genes of type A influenza viruses isolated in off-seasons and later epidemic seasons

Auteurs : S. Nakajima [Japon] ; K. Nakamura [Japon] ; F. Nishikawa [Japon] ; K. Nakajima [Japon]

Source :

RBID : ISTEX:26CBB1C82EE69C283CCE851D9E6472044FAAEB02

Abstract

From January 1985 to March 1989, off-season viruses of H1N1 and H3N2 subtypes of influenza A viruses were isolated on five occasions in Japan. The HA gene sequences of the influenza A(H1N1) and A(H3N2) viruses isolated in Japan from 1985–9 were analysed and the phylogenetic tree for each subtype virus was constructed to determine any genetic relationship between viruses isolated in off-seasons and the epidemic viruses of the following influenza seasons. In one instance with H1N1 viruses in 1986 and in two instances with H3N2 viruses in 1985 and 1987, the spring isolates were genetically close to some of the winter isolates and were considered to be the parental viruses of the following influenza seasons. However, even in these cases, influenza viruses of the same subtype with different lineages co-circulated in Japan.

Url:
DOI: 10.1017/S0950268800048536


Affiliations:


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